几何参数对主动脉支架生物力学性能的影响

doi:10.3901/JME.2021.11.112

机械工程学报 ›› 2021, Vol. 57 ›› Issue (11): 112-119.doi: 10.3901/JME.2021.11.112

• 特邀专栏：生物组织精准手术器械设计制造 • 上一篇下一篇

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几何参数对主动脉支架生物力学性能的影响

刘宗超^1,2, 吴林辉^1,2, 陈贡发^1,2

1. 广东工业大学土木与交通工程学院广州 510006;
2. 广东工业大学广东省微创手术器械设计与精密制造重点实验室广州 510006

收稿日期:2020-12-08 修回日期:2021-02-08 出版日期:2021-06-05 发布日期:2021-07-23
作者简介:刘宗超,男,1991年出生,博士研究生。主要研究方向为计算力学、生物力学和医疗器械结构优化设计。E-mail:lzc177653@163.com;陈贡发,男,1964年出生,教授,博士研究生导师。主要研究方向为生物力学、计算力学。E-mail:gongfa.chen@gdut.edu.cn
基金资助:
国家重点研发计划资助项目（2016YFE0117200）。

Influences of Geometrical Parameters on Mechanical Properties of Aortic Stent-grafts

LIU Zongchao^1,2, WU Linhui^1,2, CHEN Gongfa^1,2

1. School of Civil and Traffic Engineering, Guangdong University of Technology, Guangzhou 510006;
2. Guangdong Provincial Key Laboratory of Minimally Invasive Surgical Instruments and Manufacturing Technology, Guangdong University of Technology, Guangzhou 510006

Received:2020-12-08 Revised:2021-02-08 Online:2021-06-05 Published:2021-07-23

摘要/Abstract

摘要： 径向支撑力是评估支架在血管内移位和血管再狭窄等并发症的重要力学指标。目前针对主动脉覆膜支架的径向支撑力的研究较为少见。借助正交试验的方法，利用有限元分析全面地研究了覆膜支架主要几何参数对径向支撑力的影响。研究结果表明支架丝的直径对径向支撑力的影响最为显著，主要几何参数对支架径向支撑力的影响程度排序为：支架丝径>轴向长度>支架波峰数>波峰半径。同时径向支撑力的改变也会改变血管表面的应力环境，有可能导致血管的损伤。本研究为支架的结构优化设计具有指导意义。

关键词: 覆膜支架, 径向支撑力, 有限元分析, 正交试验

Abstract: Radial force of stent is an important mechanical index to evaluate complications such as device migration and vessel restenosis. Studies about the radial force of stent are relatively rare at present. The influence of main parameters on radial force is investigated comprehensively through the orthogonal design and finite element analysis. The results showed that the diameter of stent wire had the most significant influence on the radial force, and the influence from the main parameters on the radial force follows an order: wire diameter > axial height > strut number> strut radius. In addition, the variation of the radial force could change the stress environment on the surface of vessel, which might injure the vessel. This study has guiding significance for the design and optimization of the stent structure in the future.

Key words: stent-graft, radial force, finite element analysis, orthogonal design method

中图分类号:

TH789

刘宗超, 吴林辉, 陈贡发. 几何参数对主动脉支架生物力学性能的影响[J]. 机械工程学报, 2021, 57(11): 112-119.

LIU Zongchao, WU Linhui, CHEN Gongfa. Influences of Geometrical Parameters on Mechanical Properties of Aortic Stent-grafts[J]. Journal of Mechanical Engineering, 2021, 57(11): 112-119.

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几何参数对主动脉支架生物力学性能的影响

Influences of Geometrical Parameters on Mechanical Properties of Aortic Stent-grafts

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