• CN:11-2187/TH
  • ISSN:0577-6686

›› 2005, Vol. 41 ›› Issue (3): 185-188.

• 论文 • 上一篇    下一篇

塑料电泳芯片热键合的试验研究

于建群;刘军山;王立鼎;郭丽莎   

  1. 吉林大学生物与农业工程学院;大连理工大学机械工程学院
  • 发布日期:2005-03-15

EXPERIMENTAL STUDY ON THERMAL BONDING FOR PLASTIC CAPILLARY ELECTROPHORESIS CHIPS

Yu Jianqun;Liu Junshan;Wang Liding;Guo Lisha   

  1. School of Biological and Agricultural Engineering, Jilin University School of Mechanical Engineering,Dalian University of Technology
  • Published:2005-03-15

摘要: 塑料电泳芯片具有绝缘性、透光性好、价格便宜、成型容易和批量生产成本低等优点,是一种新型微型分析装置。研究塑料电泳芯片热键合工艺过程和工艺参数,通过试验建立微通道变形与热键合温度、压力、时间和模压工艺参数的关系,由此提出减小微通道变形的方法,对于完善塑料电泳芯片结构设计和制作的基本理论和基本技术具有积极意义。

关键词: 电泳芯片, 热键合, 生物芯片, 微机电系统, 微流控芯片, 微全分析系统, 微细加工

Abstract: A plastic capillary electrophoresis chip is a novel kind of miniaturized device for biochemistry analysis. The major advantages of the chip include high transmittance for light; low conductivity for electrokinetic pumping and electro- phoretic separation; low cost for high volume production and disposal and easily manufacturing for high aspect ratio of microchannels on the chip. A process of thermal bonding for plastic capillary electrophoresis chips is studied, the relationships between the changes of the dimensions of the microchannels and the process conditions of thermal bonding and hot embo- ssing, including temperature, pressure and time are established by experiment, based on these the ways to reduce the changes are proposed, which lays the foundation for basic theories and techniques of structural design and manufactures of the plastic chip.

Key words: Biochips, Capillary electrophoresis chips, MEMS, Microfabrication, Microfluidic chips, m-TAS, Thermal bonding

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