关键词: 快速原型, 生物制造, 支架, 组织工程

Abstract: Tissue engineering is an important development stage of bio-manufacturing. It constructs the tissue/organs by firstly fabricating the biomaterial scaffolds, and then planting the cells on them. The performance of the scaffold is very important to the application of tissue engineering. Compared to traditional scaffold manufacturing methods, rapid prototyping technology based on dispersed-accumulated principle manufactures scaffold that has high degree of personality: the porosity, the mechanical properties, the biocompatibility and biodegradation characteristic can be set through parameter design and material selection. Therefore it is very suitable for construction of structural tissue/organs. Here kinds of tissue engineering scaffold fabricating technologies based on rapid prototyping are introduced; their features and applications are summarized; their advantages and disadvantages are analyzed and discussed.

Key words: Bio-manufacturing, Rapid prototyping, Scaffold, Tissue engineering