关键词: 胞元理论, 骨组织建模, 经验公式, 模型评价, 生物力学

Abstract: Aimed to modeling bone biomechanics removed from soft tissue, model is analyzed by using finite element method. The process of fresh swine thighbone biomechanical modeling include 3D geometry reconstruction of femoral CT image data, grid, determination of apparent density, transverse isotropic mechanical modeling of finite element and parameter selection of biomechanical model. Parameters selecting is the key work in this process. Specially, relational model between elastic modulus and apparent density is the most important step. A defined function model between elastic modulus and apparent density is developed based on cellular theory. Then load-axial strain and load-lateral strain data are got from mechanical model analysis results of femur. Finite element analysis results from empirical formula of elastic modulus and apparent density also are got and biomechanical test data are recorded. Simulation results from two kinds of models are compared to test results. To the one fresh swine thighbone, Under the same environment, the result of contrast show axial strain error between cellular theory mechanical model and test data is 25.92, lateral error is 10.04. Cellular theory mechanical model simulation results are more similar to test data than results from empirical formula mechanical model. Cellular theory mechanical model show clear advantage in accurate and scope of application for femoral modeling.

Key words: biomechanics, bone tissue modeling, cancellular theory, empirical model, model evaluation