载能电刀仿生防粘表面技术

doi:10.3901/JME.2018.17.021

机械工程学报 ›› 2018, Vol. 54 ›› Issue (17): 21-27.doi: 10.3901/JME.2018.17.021

• 特邀专栏：精准微创手术器械创成与制造基础 • 上一篇下一篇

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载能电刀仿生防粘表面技术

刘光¹, 张鹏飞¹, 陈华伟¹, 韩志武², 张德远¹

1. 北京航空航天大学机械工程及自动化学院北京 100191;
2. 吉林大学工程仿生教育部重点实验室长春 130022

收稿日期:2018-01-04 修回日期:2018-05-05 出版日期:2018-09-05 发布日期:2018-09-05
通讯作者: 陈华伟(通信作者),男,1975年出生,博士,教授,博士研究生导师。主要研究方向为仿生微纳制造、界面摩擦、防冰减阻。E-mail:chenhw75@buaa.edu.cn
作者简介:刘光,男,1988年出生,博士研究生。主要研究方向为仿生与微纳米制造技术。E-mail:liuguang0701@163.com;韩志武,男,1969年出生,博士,教授,博士研究生导师。主要研究方向为工程仿生学。E-mail:zwhan@jlu.edu.cn;张德远,男,1963年出生,博士,教授,博士研究生导师。主要研究方向为振动切削加工,仿生生物制造。E-mail:zhangdy@buaa.edu.cn
基金资助:
国家自然科学基金资助项目（51290292，51725501）。

Bio-inspired Anti-adhesion Surfaces of Electrosurgical Scalpel

LIU Guang¹, ZHANG Pengfei¹, CHEN Huawei¹, HAN Zhiwu², ZHANG Deyuan¹

1. School of Mechanical Engineering and Automation, Beihang University, Beijing 100191;
2. Key Laboratory of Bionic Engineering, Ministry of Education, Jilin University, Changchun 130022

Received:2018-01-04 Revised:2018-05-05 Online:2018-09-05 Published:2018-09-05

摘要/Abstract

摘要： 微创手术具有创伤小、疼痛轻、恢复快等优点已逐渐成为外科手术主流。微创手术组织的切割、止血常采用载能手术器械如电刀、电凝钩来完成，组织粘刀严重，会引起结痂、粘刀撕裂，造成二次创伤引起医疗事故。如何解决载能手术刀粘刀是微创手术器械面临的重要技术难题，本研究师法自然，从自然中汲取表面超滑防粘创新灵感，在揭示猪笼草湿滑防粘机制的基础上，提出液膜式防粘新策略，研究了仿生防粘表面结构高温防粘机理以及制备工艺方法。通过软组织载能切削试验测试了仿生防粘表面防粘性能、以及组织热损伤与耐久性，试验结果证实了仿生防粘表面的防粘效果得到显著提升，组织粘附力降低80%、组织粘附量降低88%、创口损伤面积减小82.6%、热损伤面积减小71%，满足了载能微创手术器械防粘技术要求。

关键词: 防粘, 仿生表面, 微创手术, 载能电刀

Abstract: Minimally invasive surgery with the advantages of less trauma, slight pain and quicker recovery has gradually become the mainstream of surgical operation. Surgical tissue cutting and hemostasis are usually accomplished via energy-based surgical instruments such as monopole electrode and electric coagulation. However due to high working temperature, tissue adhesion on the surface of the electrode can char the soft tissue and result in failure of hemostasis. Under the inspiration of nature surface, the ultra-slippery feature of Nepenthes peristome and its slippery mechanism are investigated. After revealing the ultra-slippery anti-adhesion mechanism, a new strategy of liquid thin film induced anti-adhesion are put forward based on the research of biomimetic anti-adhesion surface structure and high temperature resistance method. Finally, the energy-based cutting experiments reveal that the anti-adhesion ability of as-prepared biomimetic surface is significantly improved, for example tissue adhesion force decline by 80% and 87% for tissue adhesion mass reducing, 82.6% for wound damage area reducing, 71% for thermal damage area reducing. The bio-inspired adhesion surface satisfied the requirements of energy conservation minimally invasive surgical equipment anti sticking technology.

Key words: anti-adhesion, bio-inspired surface, electrosurgical scalpel, minimally invasive surgery

中图分类号:

TH777

刘光, 张鹏飞, 陈华伟, 韩志武, 张德远. 载能电刀仿生防粘表面技术[J]. 机械工程学报, 2018, 54(17): 21-27.

LIU Guang, ZHANG Pengfei, CHEN Huawei, HAN Zhiwu, ZHANG Deyuan. Bio-inspired Anti-adhesion Surfaces of Electrosurgical Scalpel[J]. Journal of Mechanical Engineering, 2018, 54(17): 21-27.

参考文献

[1] SHAMIM M. Diathermy vs. scalpel skin incisions in general surgery:Double-blind,randomized,clinical trial[J]. World J. Surg.,2009,33:1594-1599.
[2] SIBBONS P,SOUTHGATE A. Comparison of wound-healing and tissue effects using the Gyrus plasma knife with monopolar,coblation,and harmonic scalpel methodologies[J]. Comparative Clinical Pathology,2006,15(1):17-26.
[3] SCHEMMEL M,HAEFNER H K,SELVAGGI S M,et al. Comparison of the ultrasonic scalpel to CO₂ laser and electrosurgery interms of tissue injury and adhesion formation in a rabbit model[J]. Fertil. Steril,1997,67:382-386.
[4] BRILL A I. Bipolar electrosurgery:Convention and innovation[J]. Clin. Obstet. Gynecol.,2008,51:153-158.
[5] NADER N M,NED C,DOUGLAS P S,et al. Electrosurgery:History,principles,and current and future uses[J]. J. Am. Coll. Surg.,2006,202(3):520-530.
[6] 崔明君,任思明,樊小强,等. 调制比对多层DLC涂层摩擦及电化学行为的影响[J]. 机械工程学报,2018,54(6):25-31. CUI Mingjun,REN Siming,FAN Xiaoqiang,et al. Influence of modulation ratio on the tribological and electrochemical behaviors of multilayer DLC coatings[J]. Journal of Mechanical Engineering,2018,54(6):25-31.
[7] LIN Lihsiang,HSU Yaju,CHIANG Hsijen,et al. The application of minimally invasive devices with nanostructured surface functionalization:Anti-sticking behavior on devices and liver tissue interface in rat[J]. Journal of Nanomaterials,2015,16(1):1-9.
[8] SHEN Yundun,LIN Lihsiang,CHIANG Hsijen,et al. Research of electrosurgical unit with novel antiadhesion composite thin film for tumor ablation:Microstructural characteristics,thermal conduction properties,and biological behaviors[J]. Journal of Biomedical Materials Research B:Applied Biomaterials,2016,1:96-105.
[9] OU Kengliang,CHU J,HOSSIEN H,et al. Biomedical nanostructured coating for minimally invasive surgery devices applications:Characterization,cell cytotoxicity evaluation and an animal study in rat[J]. Surg. Endosc.,2014,28:2174-2188.
[10] PAXTON J,JANNE H,CHRISTIAN S,et al. Achieving a slippery,liquid-infused porous surface with anti-icing properties by direct deposition of flame synthesized aerosol nanoparticles on a thermally fragile substrate[J]. Appl. Phys. Lett.,2017,110:1616031-1616034.
[11] 李国禄,李楠楠,王海斗,等. 不同喷涂工艺制备的Al₂O₃-13%TiO₂涂层表面自由能与冲蚀磨损性能研究[J]. 机械工程学报,2016,52(10):59-66. LI Guolu,LI Nannan,WANG Haidou,et al. Research on surface free energy and erosion wear property of Al₂O₃-13%TiO₂ coatings prepared by different spraying processes[J]. Journal of Mechanical Engineering,2016,52(10):59-66.
[12] HAN Zhiwu,FU Jia,FANG Yuqiang,et al. Anti-adhesive property of maize leaf surface related with temperature and humidity[J]. Journal of Bionic Engineering,2017,14:540-548.
[13] ZHAO Kang,LUO Defu,TANG Yufei,et al. Sol-gel derived TiO₂-bioactive glass-hydroxyapatite bioactive coating on titanium alloy substrate[J]. Journal of Mechanical Engineering,2010,23(2):263-268.
[14] LEE J,GO A,OH S,et al. Tissue anti-adhesion potential of ibuprofen-loaded PLLA-PEG diblock copolymer films[J]. Biomaterials,2005,26:671-678.
[15] LEE M,HUNG C,CHENG J,et al. A new anti-adhesion film synthesized from polygalacturonic acid with 1-ethyl-3-(3-dimethylamin-opropyl) carbodiimide crosslinker[J]. Biomaterials,2005,26:3793-3799.
[16] YANG Dejuan,CHEN Fang,XIONG Zhuochun,et al. Tissue anti-adhesion potential of biodegradable PELA electrospun membranes[J]. Acta Biomaterialia,2009,5:2467-2474.
[17] CHENG Chungwei,LIN Cenying,TSENG Wengpeng,et al. Electrosurgical unit with micro/nano structure and the manufacturing method thereof:US,US20130138103A1[P]. 2013-05-30.
[18] WU Shaofeng,GAO Dianrong,LIANG Yingna,et al. Influence of non-smooth surface on tribological properties of glass fiber-epoxy resin composite sliding against stainless steel under natural seawater lubrication[J]. Journal of Mechanical Engineering,2015,28(6):1171-1176.
[19] CHEN Huawei,ZHANG Pengfei,ZHANG Liwen. Continuous directional water transport on the peristome surface of Nepenthes alata[J]. Nature,2016(532):85-89.
[20] CUI Ying,LI Dewen,BAI Hao. Bioinspired smart materials for directional liquid transport[J]. Industrial & Engineering Chemistry Research,2017,17(56):4887-4897.
[21] ZHANG Pengfei,ZHANG Liwen,CHEN Huawei,et al. Surfaces inspired by the nepenthes peristome for unidirectional liquid transport[J]. Advanced Materials,2017,1702995:1-7.
[22] CHEN Huawei,ZHANG Liwen,ZHANG Pengfei,et al. A novel bioinspired continuous unidirectional liquid spreading surface structure from the peristome surface of nepenthes alata[J]. Small,2017,13:1-6.
[23] LI Chuxin,LI Ning,ZHANG Xinshi,et al. Uni-directional transportation on peristome-mimetic surfaces for completely wetting liquids[J]. Angew. Chem.,2016,128:15212-15216.
[24] 陈华伟,张鹏飞,张力文,等. 猪笼草口缘区表面液体单方向连续搬运机制[J]. 中国科学基金,2016(3):217-219. CHEN Huawei,ZHANG Pengfei,ZHANG Liwen,et al. Continuous directional water transport on the peristome surface of nepenthes alata[J]. Science Foundation in China,2016(3):217-219.
[25] NGUYEN P,NOBUYUKI M. Fabrication of high aspect ratio silicon micro-/nano-pore arrays and surface modification aiming at long lifetime liquid-infused-type self-cleaning function[J]. Journal of Advanced Mechanical Design,Systems,and Manufacturing,2017,2(11):1-10.
[26] KIM P,KREDER M J,ALVARENGA J,et al. Hierarchical or not? Effect of the length scale and hierarchy of the surface roughness on omniphobicity of lubricant-infused substrates[J]. Nano Letters,2013,13(4):1793-1799.
[27] KULKARNI S A,MIRJI S A,MANDALE A B,et al. Thermal stability of self-assembled octadecyltrichlorosilane monolayers on planar and curved silica surfaces[J]. Thin Solid Films,2006,496(2):420-425.
[28] ZHANG Pengfei,CHEN Huawei,ZHANG Liwen,et al. Stable slippery liquid-infused anti-wetting surface at high temperatures[J]. Applied Surface Science,Journal of Materials Chemistry A,2016,4:12212-12220.
[29] ZHANG Pengfei,CHEN Huawei,ZHANG Liwen,et al. Anti-adhesion effects of liquid-infused textured surfaces on high-temperature stainless steel for soft tissue[J]. Applied Surface Science,2016,385:249-256.

载能电刀仿生防粘表面技术

Bio-inspired Anti-adhesion Surfaces of Electrosurgical Scalpel

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