• CN:11-2187/TH
  • ISSN:0577-6686

机械工程学报 ›› 2018, Vol. 54 ›› Issue (20): 52-58.doi: 10.3901/JME.2018.20.052

• 流体生物医学工程 • 上一篇    下一篇

计算流体力学方法分析一例喷射悬浮血泵的液力、悬浮及溶血特性

武悦1,2,3, 朱良凡1,2, 罗云1,2   

  1. 1. 上海交通大学生物医学制造与生命质量工程研究所 上海 200240;
    2. 上海交通大学机械系统与振动国家重点实验室 上海 200240;
    3. 上汽大众汽车股份有限公司 上海 201805
  • 收稿日期:2017-12-05 修回日期:2018-06-12 出版日期:2018-10-20 发布日期:2018-10-20
  • 通讯作者: 罗云(通信作者),男,1963年出生,博士,教授,博士研究生导师。主要研究方向为医工交叉领域中的生物医学制造与微创医疗技术领域。E-mail:luoyun@sjtu.edu.cn
  • 作者简介:武悦,女,1989年出生,博士。主要研究方向为心室辅助装置。E-mail:dennism@sjtu.edu.cn
  • 基金资助:
    国家自然科学基金(50821003)和上海市科委(15441905200)资助项目。

Computational Fluid Dynamics Analysis of an Injection Suspension Blood Pump on the Hydraulic, Suspension and Hemolysis Property

WU Yue1,2,3, ZHU Liangfan1,2, LUO Yun1,2   

  1. 1. Institute of Biomedical Manufacturing and Life Quality Engineering, Shanghai Jiao Tong University, Shanghai 200240;
    2. State Key Laboratory of Mechanical System and Vibration, Shanghai Jiao Tong University, Shanghai 200240;
    3. SAIC Volkswagen Automotive Company Limited, Shanghai 201805
  • Received:2017-12-05 Revised:2018-06-12 Online:2018-10-20 Published:2018-10-20

摘要: 左心室辅助装置被用于治疗严重的心力衰竭,目前第三代左心室辅助装置采用液力悬浮或磁力悬浮手段,让转子悬浮在腔室中,从而完全避免机械磨损。然而,磁力悬浮需要主动控制和额外能耗,不利于长时间续航。而液力悬浮轴承间隙很小(通常小于100 μm),在这一微小间隙中,会产生高切应力和滞流点,从而造成血液损伤。为此设计一种采用新型喷射悬浮手段的血泵。该悬浮手段为被动式,且几乎没有额外的能量损耗。运用流体力学方法分析这一血泵的液力、悬浮和血液相容性能,进行试验验证,并对比新型悬浮血泵和没有喷射流道的参照泵的血液相容性。研究显示,喷射悬浮方式可以在较大的间隙下有效实现转子悬浮,且具有良好的血液相容性,对左心室辅助装置的发展有重要意义。

关键词: 计算流体力学, 喷射悬浮, 溶血性能, 旋转血泵, 左心室辅助装置

Abstract: Left ventricular assist devices (LVADs) have been developed to treat severe heart failure. Nowadays the third-generation LVADs apply either hydrodynamic or magnetic suspension method to avoid mechanical wearing. However, the magnetic suspension needs complex control system and extra energy consumption, which is not beneficial for long battery life. The hydrodynamic suspension occupies narrow gaps (usually less than 100 μm), where high shear stress and stagnant points would occur, which would cause blood damage. A blood pump using a novel injection suspension method to levitate the rotor is developed. The injection suspension method is passive and needs little extra energy consumption. The hydraulic, suspension and hemolysis property of the pump were investigated using CFD methods. Validation experiments are conducted. The hemolysis property of the novel pump and a reference pump without injection channels are compared. The results indicate that the injection suspension method could effectively levitate the rotor with a wider gap, and it has good hemocompatibility. The novel injection suspension method has important significance for the future LVAD development.

Key words: blood damage, computational fluid dynamics, injection suspension, left ventricular assist devices, rotary blood pumps

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