Abstract: As an important part of the third industrial revolution, digital manufacturing has become a powerful driving force to promote the development of manufacturing in the 21st century. The relevant theories and technologies of digital manufacturing have been gradually integrated into the product life cycle and become an indispensable driving force in the product life cycle. Based on the background of digital manufacturing science and technology, the concept of digital manufacturing and the theoretical basis of digital manufacturing, the scientific system and technology framework of digital manufacturing are put forward, and the fundamental theories and key technologies of digital manufacturing science are elaborated. Its scientific system includes computational geometry of digital manufacturing, informatics of digital manufacturing, modeling of digital manufacturing, mechanical dynamics of digital manufacturing, intelligence of digital manufacturing, bio-manufacturing of digital manufacturing, measurement error and reliability theory of digital manufacturing, technology management of digital manufacturing, etc. The technology framework of digital manufacturing includes design technology, process technology, control technology, machining technology, manufacturing resource sharing technology, condition monitoring technology, management technology, marketing and service technology, etc. Finally, the frontiers of digital manufacturing and its application prospects are discussed.

Key words: digital manufacturing, scientific system, technology framework, digital twin, manufacturing metaverse