Design of Cell in Situ Culture System for Magnetic Propelled Micro-nanorobot

doi:10.3901/JME.2022.01.001

Abstract

Abstract: As an important research direction of the new robot, micro/nano robots have made a lot of achievements in the field of biomedicine. Especially micro/nano robots driven by the magnetic field are widely used in drug delivery because of its precise motion control and no direct contact with the controlled object. In recent years, due to the lack of in-situ culture system which can control the motion of magnetically driven micro-nano robots and provide suitable temperature environment for cell tissue at the same time, the application and research of micro/nano robots in promoting cell tissue regeneration are seriously restricted. A set of cells in situ culture system for magnetically driven micro-nano robots is designed to realize the in-situ culture and monitoring of cell tissue in the experiment of magnetically driven micro/nano robots. The temperature output of the system is realized by using the principle of air-cooled radiator in reverse. The non-isothermal flow simulation is carried out by COMSOL software. These simulation results show that the heating effect of the heating module and the heating capacity of the heating actuator could meet the demand. At the same time, the position of the inlet and outlet of the incubator was defined by these. Then the temperature control experiment verified that the system could achieve stable temperature control. The design of the system has strong practicability, wide applicability and guiding significance for the research of micro/nano robots in situ culture system.

Key words: in situ culture system, magnetically driven micro-nano robots, non-isothermal flow simulation, temperature control

CLC Number:

TG156

SUN Haoran, WANG Lin, YU Shimin, DAI Lizhou, ZHANG Guangyu, LI Tianlong. Design of Cell in Situ Culture System for Magnetic Propelled Micro-nanorobot[J]. Journal of Mechanical Engineering, 2022, 58(1): 1-9.

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