Abstract: Needle biopsy sampling is a main method to obtain bone and soft tissue tumor tissue for pathological diagnosis. The puncture needle used to realize this process is widely used in tissue sampling, local drug delivery and other medical means. The degree of lubrication and surface micro-texture of the puncture needle surface are closely related to the friction force, tissue adhesion and the bending degree of puncture needle. Optimization of the puncture needle surface can reduce the friction force, improve the deflection of puncture needle and the degree of soft tissue damage during the needle insertion. Different treatment methods are explored to apply on puncture needle surface and prepared relevant experimental materials and optimized puncture needle. Two different groups of experiments are established to investigate the various aspects influence on puncture process when use the optimized puncture and the conventional needle without surface treatment. It is showed that compared with conventional puncture needles, the addition of coating and micro-texture on the surface of puncture needle body can greatly reduce the friction force and the deflection of puncture needle during needle insertion. At the same time, it can improve the problem of tissue adhesion. The coating has an obvious effect on reducing puncture force and the existence of surface micro-texture can prevent the adhesion between tissue and needle body more effectively. The surface coating and micro-texture have similar efficiency to prevent the deflection of needle body which has a guiding significance for the development of innovative medical puncture needle.

Key words: surface optimization, puncture needle, coating, micro texture, needle insertion