Abstract: For the custom design and prototyping of micro multi-functional scaffold structure, the inverse design and preparation of flexible elastic lattice structure based on DLP(Digital light procession, DLP) rapid prototyping process was carried out. A new cell is designed based on BCC(Body center cubic, BCC) cell derivation, and the mechanical model of the cell structure is established by using Timoshenko beam theory to solve its equivalent elastic modulus, and the mapping law between the geometric parameters of the cell and the mechanical model is analyzed in focus. The design of the fixed elastic modulus lattice structure under the spatial dimensional constraint is the main line, and the inverse analysis method is used to find the precise matching filling solution. A novel flexible photosensitive resin is configured as the forming material, and the DLP forming process is selected to achieve high precision and high efficiency in the preparation of the corresponding lattice structure. Combined with numerical simulations and physical experiments, this paper focuses on the difference between the elastic modulus of the reverse-designed lattice structure and the proposed value. The results show that the simulation and experimental results are in good agreement with the proposed values, which supports the reliability of the inverse design method and can provide a theoretical basis for the subsequent development of tissue-engineered skin scaffolds.

Key words: tissue engineering scaffolds, reverse design, flexible and elastic lattice structure, equivalent mechanical models, DLP forming processes